Granules for the preparation of the suspension “Pancef” for children: instructions for use

Parents frequently seek for gentle yet effective treatments for bacterial infections in their children. One such drug is "Pancef," which can be prepared as a suspension and is sold in granule form. This antibiotic helps children recover faster from respiratory, ear, and urinary infections. It is frequently prescribed.

To make sure "Pancef" functions as intended, parents must know how to use it correctly. An understanding of the appropriate dosage, suspension preparation, and possible side effects can significantly impact your child’s healing process.

We’ll go over all you need to know about using "Pancef" granules for kids in this post, so you can give them to your child with confidence. Let’s examine the salient features of this drug and its safe administration.

Release form

Granules that are yellow in color are called "Pancef," and they are used to prepare the suspension. They are put inside aluminum-topped glass bottles that have a plastic measuring cap fastened to them. One bottle contains either 32 g or 53 g of the medication.

After diluting the medication from this quantity of granules, 60 or 100 milliliters of a uniform white-yellow or white suspension with an orange scent are produced, respectively. Additionally, coated tablets of "Pancef" are available.

Composition

Cefixime in the form of trihydrate is the primary ingredient in the granules. The drug’s dosage after the suspension is prepared is 100 mg/5 ml. The medication also includes xanthan gum and sodium benzoate. Sucrose gives the final suspension its sweetness, and orange flavoring—which is included in the composition—gives it its orange taste and aroma.

Principle of action

The antibiotic "Pancef" is a third-generation member of the cephalosporin family. It acts on a variety of pathogens with a fairly broad spectrum, and it has bactericidal effects on microbes. Cefixime’s capacity to obstruct bacterial cells’ membrane synthesis process is linked to this property, which causes microorganisms to perish.

"Pancef" is very effective against the following microorganisms:

• Pneumococcus.
• Pyogenic streptococcus.
• Haemophilus influenzae.
• Moraxella catarrhalis.
• Escherichia coli.
• Gonococcus.
• Proteus.
• Various types of Klebsiella.
• Pasteurella.
• Salmonella.
• Citrobacter.
• Serratia.
• Providence.
• Shigella.

Nevertheless, the majority of enterobacteria, bacteroids, clostridia, and staphylococci are not killed by such a medication. Certain strains of acinetobacter, pseudomonas, enterococci, streptococci, and listeria have also been shown to be resistant to the effects of cefixime.

Cefixime enters the bloodstream 40–50% of the total dose after being taken orally.

When you take the medication with food, the rate of absorption will increase.

Urine is primarily where the drug is eliminated. "Pancef" should only be taken once daily due to its prolonged half-life and maximum content in plasma.

Indications

Granules are used to treat infections brought on by bacteria that respond well to cefixime. The following symptoms are treated with the medication:

• For pharyngitis, sinusitis, inflammation of the adenoids, tonsillitis, inflammation of the middle ear and other infections that are localized in the upper respiratory tract and ENT organs.
• For tracheobronchitis, pneumonia or bronchitis.
• For bacterial infection of the urinary tract.
• For uncomplicated gonorrhea.

Granules used to prepare the "Pancef" suspension are a convenient and accurate way to administer an effective medication for treating infections in children. This article will walk parents through the simple process of combining the granules with water to make a suspension, emphasize crucial usage guidelines, and go over crucial safety advice to guarantee the medication is given appropriately and safely to get the best health outcomes for their child.

From what age is it prescribed?

Granules of "Pancef" can be given to children as early as six months of age. Giving the baby such a suspension is not advised if he is not yet six months old. This medication is typically used up until the age of twelve because teenagers can already take "Pancef" tablets. However, adults and patients older than 12 are not prohibited from using the medication.

Contraindications

Children who have experienced hypersensitivity to antibiotics belonging to the cephalosporin or penicillin groups should not be administered "Pancef." The suspension is administered cautiously in cases of renal failure or colitis.

Side effects

Among the adverse effects that could happen are the following:

• The drug can cause urticaria, fever, itching of the skin, redness and other types of allergic reactions.
• Treatment with the suspension may be accompanied by abdominal pain, nausea, constipation, dysbacteriosis, vomiting, diarrhea, cholestasis, stomatitis or the appearance of jaundice.
• Due to the use of "Pancef", hematopoiesis may be inhibited, which leads to a decrease in the number of blood cells and bleeding.
• In a biochemical blood test, such indicators as urea, bilirubin, transaminases and creatinine may increase.
• In some patients, the drug causes tinnitus, dizziness, headaches.
• In rare cases, the suspension causes nephritis, shortness of breath, candidiasis or hypovitaminosis B.

Instructions for use

Since the prepared medication has a limited shelf life, the granules should be diluted with water before use.

In order to achieve a homogenous suspension, 40 ml (32 g of granules) or 66 ml (53 g of medication) of cooled, boiled water should be added to the bottle.

Water is added with a measuring cap, and it is poured in two stages, shaking the closed bottle firmly after each dilution.

The cap that comes with the bottle is used to dose the finished medication as well. It is necessary to wash and dry this cap after the child has consumed the suspension. The contents of the bottle need to be shaken before each use.

Pancef treatments typically last between seven and ten days. The daily dosage of the medication can be split into two doses or taken all at once. The suspension dosage for a child between the ages of six months and twelve years who weighs less than fifty kilograms is determined by his body weight. 8 mg/kg is prescribed daily for such a patient; this can be taken as a single dose or as two doses of 4 mg/kg.

A table listing the approximate dosages according to the baby’s weight is also included in the annotation to the granules. The child receives 400 mg of cefixime per day, or 20 ml of suspension, if he is older than 12 years old. Moreover, 10 ml of the medication (200 mg of the active ingredient) may be taken twice daily.

Overdose

In the event that a minor inadvertently consumes an excessive amount of the suspension, adverse effects may manifest or worsen. Gastric lavage should be used to treat an overdose, and symptomatic medication should be recommended.

Compatibility with other drugs

It’s crucial to think about how the medication interacts with other medications:

• When using indirect anticoagulants, their action intensifies.
• The combination with drugs that reduce the channelcial secretion increases the toxicity of the “pante”, as they delay its elimination from the body.
• Reception with antacids will slow down the absorption.
• If you use Karbamazepine together with the Panteum, its concentration will increase.

Sale conditions

In order to buy panteen granules at a pharmacy, a doctor’s prescription is required. One bottle costs between 280 and 450 rubles, depending on the volume of the finished suspension.

Storage features

The sealed bottle of Pantef has a three-year shelf life, but if you make a suspension out of granules, you can keep it in storage for up to 14 days after the date of the water dilution. You can store the medication at room temperature in your home, making sure it is out of reach from young children.

Reviews

The majority of positive reviews for panteen granules in children’s health describe the drug as convenient and effective.

The majority of babies do not object to such an antibiotic because of its tasty nature. Mothers also appreciate that this medication is only to be administered once daily.

The suspension’s short shelf life and frequent occurrence of adverse reactions, such as allergies manifesting as a rash or liquid stool, are among its drawbacks.

Furthermore, some mothers think the "pantus" is pricey. Additionally, parents complain that even the largest bottle of one course is insufficient if their child weighs more than 25 kg.

Aspect	Description
Active Ingredient	Cefixime
Dosage Form	Granules for suspension
Use	Treats bacterial infections in children
Age Range	From 6 months and older
How to Take	Mix with water to make a suspension, follow doctor’s dosage
Storage	Keep in a cool, dry place, away from sunlight
Common Side Effects	Diarrhea, nausea, rash
Precautions	Consult a doctor if allergic to antibiotics

Knowing how to take drugs like Pancef correctly can have a significant impact on how well your child is treated. The suspension granules are made to be simple to combine and give, so your child will receive the recommended dosage in a form that is easy on their stomach.

Make sure you’re correctly preparing the suspension by always paying close attention to the instructions. Ensuring your child takes the right amount of medication requires precise measurement and mixing. Please don’t hesitate to ask your healthcare provider any questions or concerns you may have.

Remember that for the medication to be effective, adhering to the prescribed dosage schedule and finishing the entire course of treatment are necessary. You can facilitate a quicker and more comfortable recovery for your child by adhering to these guidelines.

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