Polyoxidonium suppositories for children

Children are frequently prescribed polyoxidonium suppositories to strengthen their immune systems, particularly during periods when they are more prone to infections. These suppositories help children more easily fend off common illnesses like colds and the flu by bolstering the body’s natural defenses.

When searching for strategies to improve their child’s health, especially during the winter months or when their child seems to be sick all the time, parents may come across Polyoxidonium. It is a well-liked option in pediatric care since it helps children recover from illnesses more quickly in addition to preventing them from getting sick in the first place.

Being aware of the advantages, side effects, and correct usage of these suppositories can help you better manage your child’s health. Everything you need to know about Polyoxidonium suppositories, including when to use them and what to anticipate, will be covered in this article.

Dosage form and composition

Polyoxidonium is a product of the Russian company Petrovax Pharm and, in addition to suppositories, is available in two other forms – vials with lyophilisate and tablets. Polyoxidonium suppositories are characterized by an elongated shape, light yellow color and a uniform structure. Due to the presence of cocoa butter in the composition, they have a unique aroma. The medicine is sold in boxes of 10 suppositories, and inside the package there are two blisters made of a polyvinyl chloride shell, containing 5 suppositories. The main component of the drug, like other forms, is azoximer bromide. One suppository contains it in a dose of 6 mg or 12 mg. In addition to cocoa butter, two more auxiliary ingredients are added to the active substance – mannitol and povidone k17. They help to create the desired structure of the suppository and prevent its deterioration during storage.

Principle of action

• The immunomodulatory effect of the drug is associated with the ability to increase the activity of natural killers and phagocytes, as well as stimulate the synthesis of interferons and antibodies.
• The antioxidant properties of the drug are due to its special structure, since due to the high-molecular nature of the azoximer, it intercepts free radicals.
• Suppositories have a detoxifying effect, as they are able to block various toxins and activate their elimination.
• The drug also has an anti-inflammatory effect, as it normalizes the ratio of cytokines.

The body becomes more resilient to bacterial, fungal, and viral infections when suppositories are used. Furthermore, the medication aids in the recovery of immunity in cases of secondary immunodeficiencies brought on by wounds, surgeries, or infectious illnesses.

Azoximer bromide is absorbed from the gut to a degree of roughly 70% following the introduction of a suppository, and an hour later the blood concentration of this substance reaches its peak. It impacts various tissues, does not build up, and exits the body as urine after becoming low-molecular substances.

Indications

When suppositories are prescribed, they are typically part of a complex medication regimen that includes multiple medications. This particular form of polyoxidonium is recommended for therapeutic purposes:

• for acute infectious and inflammatory diseases of various origins (caused by bacteria, fungi or viruses) and different localizations;
• for chronic infections with relapses during their exacerbation;
• for an inflammatory process that is localized in the pelvic organs, for example, with cystitis or urethritis;
• for tuberculosis in various forms;
• for complications of an allergic disease with an infection, for example, with atopic dermatitis;
• to accelerate tissue regeneration processes in trophic ulcers, burns or fractures;
• for complications of rheumatoid arthritis with an infection;
• for radiation therapy or chemotherapy of oncological processes.

If suppositories containing Polyoxidonium are recommended for prophylaxis, monotherapy (taking this medication exclusively) can be utilized to prevent:

• infection with the flu;
• relapse of herpetic lesions of the genitourinary tract;
• exacerbation of a chronic infection;
• development of acute respiratory viral infections during an epidemic of such diseases;
• occurrence of secondary immunodeficiency.

From what age is it prescribed?

For children, only suppositories containing a 6 mg dosage should be used. Such Polyoxidonium is allowed beginning at age six.

Suppositories are swapped out for lyophilisate (which can be injected or drip started as early as six months) or tablets (which are prescribed for kids older than three) if the medication needs to be given to a younger child, say, four or five years old.

Contraindications

There is no use of polyoxidonium if the child

• has been found to be intolerant to azoximer bromide or another component of suppositories;
• has been diagnosed with acute renal failure.

The decision regarding Polyoxidonium treatment for small patients with chronic renal failure is made on an individual basis.

Side effects

Following suppository insertion, some patients experience excruciating itching or a reddening or swelling of the area surrounding the anus. This is how drug hypersensitivity presents itself, so if these signs appear, stop taking Polyoxidonium right away.

Instructions for use

While suppositories can be used vaginally or rectally, in childhood, such a medication is only used rectally. The rectum is filled with the suppository following an enema or spontaneous bowel movements. For a child older than six, one suppository containing six milligrams of azoximer bromide constitutes a single dose.

The use of schemes varies according to the purpose of the appointment. Typically, the medication is taken once a day for ten days, or ten suppositories. A program like this is needed for burns, trophic skin lesions, acute infectious diseases, allergies, injuries, and the aggravation of urological pathologies.

This is the method by which suppositories are recommended during the winter-spring season, when the epidemiological environment is not conducive, to prevent acute respiratory viral infections or the flu.

The practice of placing suppositories for three days straight and then continuing every other day is not any less popular. The most common use for this course, which also comes with ten suppositories, is to treat exacerbations of chronic foci of infection, like tonsillitis.

Polyoxidonium is used in a similar fashion to treat pulmonary tuberculosis; however, the course of treatment consists of 20 suppositories in total. Following the completion of the course, the medication may be prescribed for maintenance, one suppository administered twice a week for two to three months.

When a child’s rheumatoid arthritis becomes worse due to an infection, ten suppositories are administered every other day. The same 20-day program is also used to stop herpes outbreaks and other chronic infectious disease exacerbations.

When starting chemotherapy or radiation therapy, patients prescribed Polyoxidonium 1 suppository should start administering it two to three days in advance. After that, the medication should be taken twice a week. Ten suppositories are typically used for the duration of the course.

Children’s immune-stimulating medications such as polyoxidonium suppositories are commonly used to improve the body’s natural defenses against infections. They are especially helpful for children who are prone to illness, have long-term medical conditions, or require extra assistance during the flu and cold seasons. These suppositories are generally well-tolerated, simple to use, and can work well as a component of a more comprehensive treatment strategy. To ensure safe and effective results, parents should speak with a pediatrician prior to using them. Appropriate dosage and medical supervision are essential.

Overdose and drug interactions

Supositories don’t contain an excess of Polyoxidonium because they aren’t used in multiple doses at once. Regarding interactions with other medications, Polyoxidonium may be taken with a wide range of medications, such as antiviral, antihistamine, and antibiotic medications, according to the manufacturer.

Terms of sale and storage

Since polyoxidonium in suppositories is an over-the-counter medication, many pharmacies readily stock it. A package of suppositories typically costs between 850 and 900 rubles.

The medication’s two-year expiration date is stated on the box. At home, suppositories should be kept between +2 and +15 degrees Celsius in a cool place.

Reviews

Suppositories are generally recommended for children by doctors and parents. Immunologists list several uses for this type of Polyoxidonium as well as the child’s body’s safety.

Mothers attest that this medication’s therapeutic benefits materialize rapidly, with its primary drawback being its exorbitant cost.

Supplets containing polyoxidonium may be a beneficial choice for bolstering a child’s immune system, particularly if the child experiences frequent illnesses. They provide a convenient means of giving medication to children who might have difficulty swallowing pills or liquids, and they are generally well-tolerated.

But as with any medication, it’s crucial to take Polyoxidonium suppositories under a doctor’s supervision. They can determine whether this treatment is suitable for the unique medical requirements of your child and keep an eye out for any possible adverse effects.

All things considered, these suppositories may help your child’s immune response, but they should only be used in conjunction with a more comprehensive approach to health that includes a balanced diet, frequent exercise, and proper hygiene. To find the best course of action for your child’s health, always consult your physician.

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