When and how to properly stop taking Duphaston during pregnancy?

For expectant mothers, determining when and how to stop taking Duphaston during pregnancy can be a critical decision. In order to protect the health of both the mother and the fetus, this medication—which is frequently prescribed to support pregnancies, particularly in cases of progesterone deficiency—needs to be carefully managed.

It is crucial to comprehend when and how to stop taking Duphaston in order to prevent any problems. Your healthcare provider should make this decision; they will take into account things like the status of your pregnancy and any underlying medical issues that might interfere with the weaning process.

This post will go over the important things to think about when we stop taking Duphaston, such as when it might be time to stop the medication and how to do it safely. You can handle this part of your pregnancy with assurance and serenity if you listen to professional guidance and remain educated.

Features of the drug

The medication, which contains dydrogesterone as its primary ingredient, is marketed as round tablets with a white shell. This substance bears structural and functional similarities to progesterone, a hormone produced by females that aids in successful childbearing. Ten milligrams of testosterone are contained in one tablet. The medication is available only with a prescription, has a good safety record for the fetus, and can be taken at any point during pregnancy.

When is it prescribed to pregnant women?

Most often, Duphaston is prescribed to expectant mothers with a threat of miscarriage, which is manifested by increased uterine tone and bloody discharge. This situation is usually caused by a lack of progesterone, and Duphaston is designed to replace it. The drug begins to act within 2 hours after administration, eliminates dangerous symptoms and allows the pregnancy to develop normally. If a woman has had miscarriages in the past in the early stages or the pregnancy has stopped, then after determining the level of progesterone in the blood and confirming its deficiency, Duphaston is prescribed even before conception. After a positive test, the drug is not canceled, but continues to be taken throughout the first trimester or longer. In such a situation, Duphaston will prepare the inner lining of the uterus for implantation and will contribute to better fixation of the embryo. The use of tablets is also justified for various pathologies affecting the uterine lining, for example, endometriosis or fibroids. Such diseases can interfere with the attachment of the fertilized egg, therefore, after treatment with Duphaston, the probability of pregnancy increases.

The IVF protocol is another typical indication for using the medication. Duphaston boosts the likelihood of embryo implantation when employing this artificial insemination technique.

How it is used?

The tablets are taken according to an individually selected regimen, which depends on the reason for the appointment. For example, if the expectant mother suddenly experiences symptoms of a threatened miscarriage, she needs to immediately take 4 tablets, and then take 1 tablet every 8 hours until the condition normalizes. If a woman has previously had problems with bearing a child, she is prescribed a two-time dose of Duphaston, one tablet at a time, and when preparing for IVF, the drug is often taken 10 mg three times a day. These are the most common options for use, but they can change for a specific woman, taking into account her condition, age, progesterone levels and other factors.

Why is it discontinued gradually?

When a doctor prescribes Duphaston to a pregnant woman, he/she will definitely emphasize to the expectant mother that the discontinuation should be slow and careful. Particular attention should be paid to the end of the course if there is a risk of miscarriage, since abrupt discontinuation will threaten the resumption of dangerous symptoms and worsening of the condition. If the drug is prescribed for infertility, it should never be discontinued when a woman finds out that she is pregnant. If you stop taking the pills without gradual discontinuation in the first trimester, this will increase the contractile activity of the myometrium and increase the risk of rejection of the embryo, which will provoke bleeding and miscarriage. However, it is also unacceptable to discontinue the drug abruptly in the second trimester. Such actions can cause fetoplacental insufficiency, which can also result in termination of pregnancy. And therefore, it is important to discontinue the medication gradually at any time.

When can you cancel?

Duphaston therapy continues until 12 weeks of gestation, even if the expectant mother feels fine and has no complaints. Intermittent use of the medication may result in hypertension and other hazardous alterations, as the placenta is still developing and has not yet assumed the role of producing progesterone. Due to this, it is advised to use Duphaston as a natural hormone substitute during the first trimester of pregnancy. The tablets are typically stopped at 16–20 weeks because the placenta usually forms fully by the 16th obstetric week.

On the other hand, some patients need to take their medication for longer, so a gradual dose reduction doesn’t start until the 20th week or later. In any event, you should discuss with your obstetrician-gynecologist the precise timing of when you should begin lowering the dosage.

Making the right decision about when and how to stop taking Duphaston during pregnancy is essential for the health of the mother and the unborn child. Duphaston is a drug that is frequently prescribed to aid in early pregnancy. It is best to stop taking it according to your doctor’s advice, usually after determining that your pregnancy is stable. Maintaining your best health throughout your pregnancy and facilitating a seamless transition are two benefits of knowing when and how to stop taking this medication.

How to stop taking it correctly?

• for three days, take a whole tablet in the morning and only half in the evening, that is, the total amount per day will be 15 mg;
• the next three days, reduce the daily dose by another 5 mg, taking half a tablet in the morning and another half in the afternoon;
• then refuse one of the doses, leaving only the morning dose of 5 mg or taking the drug in the evening in the same dosage;
• after 3 days of taking 5 mg, refuse the drug altogether, but in some cases drink a quarter of a tablet for three more days.

The withdrawal is handled similarly if the daily dosage was 30 mg, lowering by 1 tablet every week or half every 3–4 days. It is also not advised to stop therapy abruptly if "Duphaston" did not help and the pregnancy could not be maintained.

For these patients, the daily dosage should be decreased by one tablet. If a woman took three tablets a day, for instance, she should take two tablets on the first day of cancellation, one tablet on the second, and half on the third.

Analogues

Not every woman can take Duphaston as prescribed. This medication may cause unpleasant side effects or allergic reactions in certain pregnant women. In these situations, it is also advisable to stop taking the medication and switch to a more tolerable analogue. It is best to speak with a doctor if a pregnant woman exhibits signs of hypersensitivity or other adverse reactions so that he can recommend an appropriate withdrawal schedule.

Along with lowering the dosage of Duphaston, it will also involve beginning to use Utrozhestan, an analogue of the drug. The same illnesses and ailments for which Duphaston is prescribed can also be treated with this capsule medication, which contains micronized progesterone. Furthermore, it can be inserted vaginally in addition to being taken orally, as is frequently the case in expectant mothers with severe early toxicosis or an adverse reaction of the digestive tract to Duphaston tablets.

Other progesterone-based equivalents include Crinone, Iprozhin, and Prajisan. The gynecologist supervising a pregnant woman should decide which of these medications is best for her.

A key component of prenatal care is determining when and how to stop taking Duphaston during pregnancy. It’s critical to heed the advice of your healthcare provider because they will customize it to your unique circumstances and medical background. When to stop taking Duphaston is usually determined by the length of your pregnancy as well as the reason it was prescribed in the first place.

Usually, the medication is tapered off gradually rather than stopping all at once to give your body time to adjust. If necessary, your doctor will give you instructions on how to gradually stop taking the medication while keeping a close eye on you. Any worries or negative effects you encounter during this process should always be shared.

Keep in mind that the greatest source for individualized guidance is your healthcare provider. To provide a secure and efficient method of halting Duphaston, they will take into account all relevant variables, including your health and the health of your unborn child.

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